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The Purple Guide:
Developing Your
Clinical Dental Hygiene
Career
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Amy's Class
Notes on Pharmacology -- Adregenic and Adregenic Blocking Agents (1999)
I don't know if these will
help you out but just in case, I added them onto the site. These are just
notes that I took in class in different formats.
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Adrenergic Agents -agonists (has affinity for receptor and binds to it producing an effect). -Direct action on receptor; indirectly acting release presynaptic NE: mixed – both -Pharmacologic effects * CNS *cardiovascular *eye *respiratory *metabolic effects *salivary glands -Adverse reactions *anxiety and tremors *pt. may have palpations *serious arrhythmias can result. *a(alpha) adrenergic action can increase BP -Uses Vasoconstriction 1. prolong action of local anesthetics via construction of blood vessels. aLso reduces toxic side effects. 2. Homeostasis- used topically or infiltrated locally to stop bleeding in dental field but use cautiously as can be absorbed and have toxic effects. 3. Decongestion- incorporated into nose drops or sprays (Constrict vessels and reduce swelling of nasal mucosa) Cardiac effects 1. treatment of shock – elevates BP, but need to correct the cause of shock. 2. Treatment of cardiac arrest- stimulate heart. Bronchodilation- treat asthma, emphysema, and anaphylaxis CNS stimulation- stimulation effects used in some diet pills, attention deficit disorder -Special adrenergic agents (From book) *Epinephrine *Phenylephrine *Levonordefrin *Isoproterenol *Ephedrine *Pseudoephedrine *Dopamine *Dipivefrin *Amphatimine -DRUGS *Ephinephrine * Norephinephrine *Phenylephrine *Levonordefrin *Isoproterenol *Ephedrine *Pseudoephedrine *Dopamine *Dipivefrine *Amphetamine *Albuterol *Terbutaline |
Adrenergic blocking agents -antagonists (has affinity for receptor and binds to it but produces no effect). -a(alpha)-adrenergic blocking agents -inhibit vasoconstricting effects of adrenergic agents. -Reduces sympathetic tone thus decreasing TPR. -The decrease in BP can stimulate vagus nerve and result in reflex bradycardia. -Block myadriasis. -B(Beta)-adrenergic blocking agents -generic names end in –olol -Block beta receptor stimulation and produces bradycardia, bronchoconstriction. -Non-selective and selective drugs. -a(alpha) and B(beta) blocking agents -treats hypertension without reflex tachycardia. -DRUGS *a1 blocking- Phenoxubenzamine, Phentolamine, Prazosin, Doxazosin *Nonselective B blocking- Propanol, Timolol *Selective B1 blocking- metoprolol, Atenolol, Bisoprolol *a and B blocking - Laberatol
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If you would like to help me out and add some of your class notes to help others out, please email me and I will add it to the site -- THANKS :)
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